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Symbol
Name
ID
Fech
ferrochelatase
MGI:95513
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Reduced erythrocyte uroporphyrinogen III cosynthase activity
Hemolytic anemia
Iron deficiency anemia
Microcytic anemia
Thrombocytopenia
Splenomegaly
Disease(s) Associated with FECH
cutaneous porphyria
erythropoietic protoporphyria

Mouse Phenotypes
increased spleen weight
abnormal erythropoiesis
hypochromic anemia
abnormal erythrocyte morphology
decreased erythrocyte cell number
decreased hematocrit
decreased hemoglobin content
increased red blood cell distribution width
anisocytosis
increased erythrocyte protoporphyrin level
leptocytosis
polychromatophilia
reticulocytosis
decreased erythrocyte osmotic fragility
Availability Mouse Genotype
Fechm1Pas/Fechm1Pas

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory